Biphasic Regulation of Myosin Light Chain Phosphorylation by p21-activated Kinase Modulates Intestinal Smooth Muscle Contractility

Supraphysiological mechanical stretching in smooth muscle results in decreased contractile activity. However, the mechanism is unclear. Previous studies indicated that intestinal motility dysfunction after edema development is associated with increased smooth muscle stress and decreased myosin light...

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Autori principali: Chu, Ji, Pham, Ngoc T., Olate, Nicole, Kislitsyna, Karina, Day, Mary-Clare, LeTourneau, Phillip A., Kots, Alexander, Stewart, Randolph H., Laine, Glen A., Cox, Charles S., Uray, Karen
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543003/
https://ncbi.nlm.nih.gov/pubmed/23161543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370718
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