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Decreased myosin phosphatase target subunit 1(MYPT1) phosphorylation via attenuated rho kinase and zipper-interacting kinase activities in edematous intestinal smooth muscle

BACKGROUND: Intestinal edema development after trauma resuscitation inhibits intestinal motility which results in ileus, preventing enteral feeding and compromising patient outcome. We have shown previously that decreased intestinal motility is associated with decreased smooth muscle myosin light ch...

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Bibliographic Details
Main Authors: Chu, Ji, Miller, Christopher T., Kistlitsyna, Karina, Laine, Glen A., Stewart, Randolph H., Cox, Charles S., Uray, Karen S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321580/
https://ncbi.nlm.nih.gov/pubmed/22235829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2011.01855.x
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