Hypoxia modulates the expression of leucine zipper-positive MYPT1 and its interaction with protein kinase G and Rho kinases in pulmonary arterial smooth muscle cells

We have shown previously that acute hypoxia downregulates protein kinase G (PKG) expression and activity in ovine fetal pulmonary vessels and pulmonary arterial smooth muscle cells (SMC). Here, we report that acute hypoxia also reduces the expression of leucinezipper-positive MYPT1 (LZ(+)MYPT1), a s...

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Detalhes bibliográficos
Main Authors: Singh, Dev K., Sarkar, Joy, Raghavan, Aarti, Reddy, Sekhar P., Raj, J. Usha
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329079/
https://ncbi.nlm.nih.gov/pubmed/22530104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.93548
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