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Hypoxic Regulation of Pulmonary Vascular Smooth Muscle Cyclic Guanosine Monophosphate–Dependent Kinase by the Ubiquitin Conjugating System
We previously reported that hypoxia attenuates nitric oxide–cyclic guanosine monophosphate (NO-cGMP)–mediated fetal pulmonary vessel relaxation by inhibiting cGMP-dependent protein kinase 1 (PKG1) activity, but not all the mechanisms by which acute hypoxia inhibits PKG1 activity have been delineated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326432/ https://ncbi.nlm.nih.gov/pubmed/21997485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0165OC |
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