Biphasic Regulation of Myosin Light Chain Phosphorylation by p21-activated Kinase Modulates Intestinal Smooth Muscle Contractility

Supraphysiological mechanical stretching in smooth muscle results in decreased contractile activity. However, the mechanism is unclear. Previous studies indicated that intestinal motility dysfunction after edema development is associated with increased smooth muscle stress and decreased myosin light...

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Detalhes bibliográficos
Main Authors: Chu, Ji, Pham, Ngoc T., Olate, Nicole, Kislitsyna, Karina, Day, Mary-Clare, LeTourneau, Phillip A., Kots, Alexander, Stewart, Randolph H., Laine, Glen A., Cox, Charles S., Uray, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543003/
https://ncbi.nlm.nih.gov/pubmed/23161543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370718
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