Monitoring the GAP catalyzed H-Ras GTPase reaction at atomic resolution in real time
The molecular reaction mechanism of the GTPase-activating protein (GAP)-catalyzed GTP hydrolysis by Ras was investigated by time resolved Fourier transform infrared (FTIR) difference spectroscopy using caged GTP (P(3)-1-(2-nitro)phenylethyl guanosine 5′-O-triphosphate) as photolabile trigger. This a...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2001
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35414/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.131549798 |
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