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Monitoring the GAP catalyzed H-Ras GTPase reaction at atomic resolution in real time
The molecular reaction mechanism of the GTPase-activating protein (GAP)-catalyzed GTP hydrolysis by Ras was investigated by time resolved Fourier transform infrared (FTIR) difference spectroscopy using caged GTP (P(3)-1-(2-nitro)phenylethyl guanosine 5′-O-triphosphate) as photolabile trigger. This a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC35414/ https://ncbi.nlm.nih.gov/pubmed/11438727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.131549798 |
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