Loading...

p53-Independent Roles of MDM2 in NF-κB Signaling: Implications for Cancer Therapy, Wound Healing, and Autoimmune Diseases

Murine double minute-2 (MDM2) is an intracellular molecule with multiple biologic functions. It serves as a negative regulator of p53 and thereby limits cell cycle arrest and apoptosis. Because MDM2 blockade suppresses tumor cell growth in vitro and in vivo, respective MDM2 inhibition is currently e...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Thomasova, Dana, Mulay, Shrikant R, Bruns, Hauke, Anders, Hans-Joachim
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540936/
https://ncbi.nlm.nih.gov/pubmed/23308042
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!