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Regulation of NF-κB by deubiquitinases
The nuclear factor-κB (NF-κB) pathway is a critical regulator of innate and adaptive immunity. Noncanonical K63-linked polyubiquitination plays a key regulatory role in NF-κB signaling pathways by functioning as a scaffold to recruit kinase complexes containing ubiquitin-binding domains. Ubiquitinat...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540820/ https://ncbi.nlm.nih.gov/pubmed/22435550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01100.x |
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