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Deubiquitinases in the regulation of NF-κB signaling

Nuclear factor-kappa B (NF-κB) is a critical regulator of multiple biological functions including innate and adaptive immunity and cell survival. Activation of NF-κB is tightly regulated to preclude chronic signaling that may lead to persistent inflammation and cancer. Ubiquitination of key signalin...

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Hlavní autoři: Harhaj, Edward W, Dixit, Vishva M
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075605/
https://ncbi.nlm.nih.gov/pubmed/21119682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.166
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