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In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites
Microcin B17 (MccB17) is a 3.1-kDa Escherichia coli antibiotic that contains thiazole and oxazole heterocycles in a peptide backbone. MccB17 inhibits its cellular target, DNA gyrase, by trapping the enzyme in a complex that is covalently bound to double-strand cleaved DNA, in a manner similar to the...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The National Academy of Sciences
2001
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC35407/ https://ncbi.nlm.nih.gov/pubmed/11427730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141225698 |
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