In Vivo Cardiac Cellular Reprogramming Efficacy Is Enhanced by Angiogenic Preconditioning of the Infarcted Myocardium With Vascular Endothelial Growth Factor

BACKGROUND: In situ cellular reprogramming offers the possibility of regenerating functional cardiomyocytes directly from scar fibroblasts, obviating the challenges of cell implantation. We hypothesized that pretreating scar with gene transfer of the angiogenic vascular endothelial growth factor (VE...

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Detalhes bibliográficos
Main Authors: Mathison, Megumi, P. Gersch, Robert, Nasser, Ahmed, Lilo, Sarit, Korman, Mallory, Fourman, Mitchell, Hackett, Neil, Shroyer, Kenneth, Yang, Jianchang, Ma, Yupo, Crystal, Ronald G., Rosengart, Todd K.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540681/
https://ncbi.nlm.nih.gov/pubmed/23316332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.005652
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