MicroRNA-33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE(−/−) Mice

BACKGROUND: Cholesterol efflux from cells to apolipoprotein A-I (apoA-I) acceptors via the ATP-binding cassette transporters ABCA1 and ABCG1 is thought to be central in the antiatherogenic mechanism. MicroRNA (miR)-33 is known to target ABCA1 and ABCG1 in vivo. METHODS AND RESULTS: We assessed the i...

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Detalhes bibliográficos
Main Authors: Horie, Takahiro, Baba, Osamu, Kuwabara, Yasuhide, Chujo, Yoshimasa, Watanabe, Shin, Kinoshita, Minako, Horiguchi, Masahito, Nakamura, Tomoyuki, Chonabayashi, Kazuhisa, Hishizawa, Masakatsu, Hasegawa, Koji, Kume, Noriaki, Yokode, Masayuki, Kita, Toru, Kimura, Takeshi, Ono, Koh
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540673/
https://ncbi.nlm.nih.gov/pubmed/23316322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.112.003376
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