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Structure of a Ca(2+)/CaM:Kv7.4 (KCNQ4) B helix complex provides insight into M-current modulation
Calmodulin (CaM) is an important regulator of Kv7.x (KCNQx) voltage-gated potassium channels. Channels from this family produce neuronal M-currents and cardiac and auditory I(KS) currents, and harbor mutations that cause arrhythmias, epilepsy, and deafness. Despite extensive functional characterizat...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540129/ https://ncbi.nlm.nih.gov/pubmed/23178170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.11.023 |
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