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Structural Insight into KCNQ (Kv7) Channel Assembly and Channelopathy
Kv7.x (KCNQ) voltage-gated potassium channels form the cardiac and auditory I(Ks) current and the neuronal M-current. The five Kv7 subtypes have distinct assembly preferences encoded by a C-terminal cytoplasmic assembly domain, the A-domain Tail. Here, we present the high-resolution structure of the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3011230/ https://ncbi.nlm.nih.gov/pubmed/17329207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2007.02.010 |
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