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Effects of KCNQ2 Gene Truncation on M-Type Kv7 Potassium Currents

The KCNQ2 gene product, Kv7.2, is a subunit of the M-channel, a low-threshold voltage-gated K(+) channel that regulates mammalian and human neuronal excitability. Spontaneous mutations one of the KCNQ2 genes cause disorders of neural excitability such as Benign Familial Neonatal Seizures. However th...

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Detalhes bibliográficos
Main Authors: Robbins, Jon, Passmore, Gayle M., Abogadie, Fe C., Reilly, Joanne M., Brown, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3748097/
https://ncbi.nlm.nih.gov/pubmed/23977150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071809
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