Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization

Since prostate cancer (CaP) is regulated by androgen receptor (AR) activity, metastatic CaP is treated with androgen deprivation therapy (ADT). Despite initial response, patients on ADT eventually progress to castration-resistant CaP (CRPC), which is currently incurable. We previously showed that cl...

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Detalhes bibliográficos
Main Authors: Mooso, Benjamin A., Vinall, Ruth L., Tepper, Clifford G., Savoy, Rosalinda M., Cheung, Jean P., Singh, Sheetal, Siddiqui, Salma, Wang, Yu, Bedolla, Roble G., Martinez, Anthony, Mudryj, Maria, Kung, Hsing-Jien, deVere White, Ralph W., Ghosh, Paramita M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540117/
https://ncbi.nlm.nih.gov/pubmed/22993077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0171
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