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Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells

Patients with advanced prostate cancer (PCa) are initially susceptible to androgen withdrawal (AW), but ultimately develop resistance to this therapy (castration-resistant PCa, CRPC). Here we show that AW can promote CRPC development by increasing the levels of the receptor tyrosine kinase (RTK) Erb...

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Detalhes bibliográficos
Main Authors: Chen, Liqun, Siddiqui, Salma, Bose, Swagata, Mooso, Benjamin, Asuncion, Alfredo, Bedolla, Roble G., Vinall, Ruth, Tepper, Clifford G., Gandour-Edwards, Regina, Shi, XuBao, Lu, Xiao-Hua, Siddiqui, Javed, Chinnaiyan, Arul M., Mehra, Rohit, deVere White, Ralph W., Carraway, Kermit L., Ghosh, Paramita M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905475/
https://ncbi.nlm.nih.gov/pubmed/20587519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4440
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