Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells

Patients with advanced prostate cancer (PCa) are initially susceptible to androgen withdrawal (AW), but ultimately develop resistance to this therapy (castration-resistant PCa, CRPC). Here we show that AW can promote CRPC development by increasing the levels of the receptor tyrosine kinase (RTK) Erb...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Chen, Liqun, Siddiqui, Salma, Bose, Swagata, Mooso, Benjamin, Asuncion, Alfredo, Bedolla, Roble G., Vinall, Ruth, Tepper, Clifford G., Gandour-Edwards, Regina, Shi, XuBao, Lu, Xiao-Hua, Siddiqui, Javed, Chinnaiyan, Arul M., Mehra, Rohit, deVere White, Ralph W., Carraway, Kermit L., Ghosh, Paramita M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905475/
https://ncbi.nlm.nih.gov/pubmed/20587519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4440
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge