Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization

Since prostate cancer (CaP) is regulated by androgen receptor (AR) activity, metastatic CaP is treated with androgen deprivation therapy (ADT). Despite initial response, patients on ADT eventually progress to castration-resistant CaP (CRPC), which is currently incurable. We previously showed that cl...

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Hlavní autoři: Mooso, Benjamin A., Vinall, Ruth L., Tepper, Clifford G., Savoy, Rosalinda M., Cheung, Jean P., Singh, Sheetal, Siddiqui, Salma, Wang, Yu, Bedolla, Roble G., Martinez, Anthony, Mudryj, Maria, Kung, Hsing-Jien, deVere White, Ralph W., Ghosh, Paramita M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540117/
https://ncbi.nlm.nih.gov/pubmed/22993077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-12-0171
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