Nuclear vs Cytoplasmic localization of Filamin A in Prostate Cancer: Immunohistochemical Correlation with Metastases

PURPOSE: We previously showed that nuclear localization of the actin-binding protein FilaminA (FlnA) corresponded to hormone-dependence in prostate cancer (Oncogene, 2007, 26:6061-6070). Intact FlnA (280kDa, cytoplasmic) cleaved to a 90kDa fragment which translocated to the nucleus in hormone-naïve...

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Главные авторы: Bedolla, Roble G., Wang, Yu, Asuncion, Alfredo, Chamie, Karim, Siddiqui, Salma, Mudryj, Maria M., Prihoda, Thomas J., Siddiqui, Javed, Chinnaiyan, Arul M., Mehra, Rohit, deVereWhite, Ralph W., Ghosh, Paramita M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666194/
https://ncbi.nlm.nih.gov/pubmed/19188148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1402
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