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Applications of minimal physiologically-based pharmacokinetic models
Conventional mammillary models are frequently used for pharmacokinetic (PK) analysis when only blood or plasma data are available. Such models depend on the quality of the drug disposition data and have vague biological features. An alternative minimal-physiologically-based PK (minimal-PBPK) modelin...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539784/ https://ncbi.nlm.nih.gov/pubmed/23179857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-012-9280-2 |
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