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Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

DNA methylation at proximal promoters facilitates lineage restriction by silencing cell type–specific genes. However, euchromatic DNA methylation frequently occurs in regions outside promoters. The functions of such nonproximal promoter DNA methylation are unclear. Here we show that the de novo DNA...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wu, Hao, Coskun, Volkan, Tao, Jifang, Xie, Wei, Ge, Weihong, Yoshikawa, Kazuaki, Li, En, Zhang, Yi, Sun, Yi Eve
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539760/
https://ncbi.nlm.nih.gov/pubmed/20651149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190485
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