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Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation
The INK4a/ARF locus on the short arm of chromosome 9 is one of the most frequently altered loci in human cancer. It is generally accepted that ARF is involved in oncogenic checkpoint pathways by sensitizing incipient cancer cells to undergo growth arrest or apoptosis through both p53-dependent and i...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3538741/ https://ncbi.nlm.nih.gov/pubmed/23308265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053631 |
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