Mimicking p14ARF Phosphorylation Influences Its Ability to Restrain Cell Proliferation

The INK4a/ARF locus on the short arm of chromosome 9 is one of the most frequently altered loci in human cancer. It is generally accepted that ARF is involved in oncogenic checkpoint pathways by sensitizing incipient cancer cells to undergo growth arrest or apoptosis through both p53-dependent and i...

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Bibliografiske detaljer
Main Authors: Vivo, Maria, Ranieri, Michela, Sansone, Federica, Santoriello, Cristina, Calogero, Raffaele A., Calabrò, Viola, Pollice, Alessandra, La Mantia, Girolama
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538741/
https://ncbi.nlm.nih.gov/pubmed/23308265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053631
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