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Novel Protein Transduction Domain Mimics as Nonviral Delivery Vectors for siRNA Targeting NOTCH1 in Primary Human T cells

RNA interference technology has recently been highlighted as a powerful research method as well as a potential therapeutic treatment for several diseases. However, the delivery of small interfering RNA (siRNA) into T cell lines and primary blood cells is exceedingly challenging, as they are resistan...

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Detalhes bibliográficos
Main Authors: Tezgel, A. Özgül, Gonzalez-Perez, Gabriela, Telfer, Janice C., Osborne, Barbara A., Minter, Lisa M., Tew, Gregory N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538314/
https://ncbi.nlm.nih.gov/pubmed/23070119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.209
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