Vascular Injury Triggers Krüppel-Like Factor 6 (KLF6) Mobilization and Cooperation with Sp1 to Promote Endothelial Activation through Upregulation of the Activin Receptor-Like Kinase 1 (ALK1) Gene

RATIONALE: Activin receptor-Like Kinase-1 (ALK1) is an endothelial TGF-β receptor involved in angiogenesis. ALK1 expression is high in the embryo vasculature, becoming less detectable in the quiescent endothelium of adult stages. However, ALK1 expression becomes rapidly increased after angiogenic st...

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Bibliografiska uppgifter
Huvudupphovsmän: Garrido-Martín, Eva M., Blanco, Francisco J., Roquè, Mercé, Novensà, Laura, Tarocchi, Mirko, Lee, Ursula E., Suzuki, Toru, Friedman, Scott L., Botella, Luisa M., Bernabéu, Carmelo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537907/
https://ncbi.nlm.nih.gov/pubmed/23048070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.275586
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