Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury

After endothelial injury, the transcription factor Krüppel-like factor 6 (KLF6) translocates into the cell nucleus to regulate a variety of target genes involved in angiogenesis, vascular repair and remodeling, including components of the membrane transforming growth factor beta (TGF-β) receptor com...

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Publicat a:Angiogenesis
Autors principals: Gallardo-Vara, Eunate, Blanco, Francisco J., Roqué, Mercè, Friedman, Scott L., Suzuki, Toru, Botella, Luisa M., Bernabeu, Carmelo
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2016
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819519/
https://ncbi.nlm.nih.gov/pubmed/26850053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-016-9495-8
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