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Vascular Injury Triggers Krüppel-Like Factor 6 (KLF6) Mobilization and Cooperation with Sp1 to Promote Endothelial Activation through Upregulation of the Activin Receptor-Like Kinase 1 (ALK1) Gene

RATIONALE: Activin receptor-Like Kinase-1 (ALK1) is an endothelial TGF-β receptor involved in angiogenesis. ALK1 expression is high in the embryo vasculature, becoming less detectable in the quiescent endothelium of adult stages. However, ALK1 expression becomes rapidly increased after angiogenic st...

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Autori principali: Garrido-Martín, Eva M., Blanco, Francisco J., Roquè, Mercé, Novensà, Laura, Tarocchi, Mirko, Lee, Ursula E., Suzuki, Toru, Friedman, Scott L., Botella, Luisa M., Bernabéu, Carmelo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537907/
https://ncbi.nlm.nih.gov/pubmed/23048070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.275586
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