Lovastatin induced Kruppel like factor 2 (KLF2), Kruppel like factor 6 (KLF6) and Ras homolog family member B (RHOB) genes and preferentially led to viability reduction of Cisplatin-resistant cells

It was reported that statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase that are used to prevent hypercholesterolemia, have antitumor activity in several cancers. In this study, we investigated the cell viability of statins in Cisplatin-resistant HCP4 and PCDP5 cells compared wit...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Koi, Chiho, Izumi, Hiroto, Kurita, Tomoko, Nguyen, Thuy Thi, Murakami, Midori, Yoshiura, Yukiko, Hachisuga, Toru, Morimoto, Yasuo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739745/
https://ncbi.nlm.nih.gov/pubmed/29290960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22472
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