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Analysis of Replication Intermediates Indicates That Drosophila melanogaster Mitochondrial DNA Replicates by a Strand-Coupled Theta Mechanism

Mitochondrial DNA synthesis is necessary for the normal function of the organelle and for the eukaryotic organism as a whole. Here we demonstrate, using two-dimensional agarose gel electrophoresis to analyse replication intermediates, that unidirectional, strand-coupled DNA synthesis is the prevalen...

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Autores principales: Jõers, Priit, Jacobs, Howard T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537619/
https://ncbi.nlm.nih.gov/pubmed/23308172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053249
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