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Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase

Pathological conditions impairing functions of mitochondria often lead to compensatory upregulation of the mitochondrial DNA (mtDNA) replisome machinery, and the replicative DNA helicase appears to be a key factor in regulating mtDNA copy number. Moreover, mtDNA helicase mutations have been associat...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Ciesielski, Grzegorz L, Nadalutti, Cristina A, Oliveira, Marcos T, Jacobs, Howard T, Griffith, Jack D, Kaguni, Laurie S
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887560/
https://ncbi.nlm.nih.gov/pubmed/29432582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky094
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