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Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase

Pathological conditions impairing functions of mitochondria often lead to compensatory upregulation of the mitochondrial DNA (mtDNA) replisome machinery, and the replicative DNA helicase appears to be a key factor in regulating mtDNA copy number. Moreover, mtDNA helicase mutations have been associat...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Ciesielski, Grzegorz L, Nadalutti, Cristina A, Oliveira, Marcos T, Jacobs, Howard T, Griffith, Jack D, Kaguni, Laurie S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887560/
https://ncbi.nlm.nih.gov/pubmed/29432582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky094
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