Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase

Pathological conditions impairing functions of mitochondria often lead to compensatory upregulation of the mitochondrial DNA (mtDNA) replisome machinery, and the replicative DNA helicase appears to be a key factor in regulating mtDNA copy number. Moreover, mtDNA helicase mutations have been associat...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Ciesielski, Grzegorz L, Nadalutti, Cristina A, Oliveira, Marcos T, Jacobs, Howard T, Griffith, Jack D, Kaguni, Laurie S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Molecular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5887560/
https://ncbi.nlm.nih.gov/pubmed/29432582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky094
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