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Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase

The xenotopic expression of the alternative oxidase AOX from the tunicate Ciona intestinalis in diverse models of human disease partially alleviates the phenotypic effects of mitochondrial respiratory chain defects. AOX is a non-proton pumping, mitochondrial inner membrane-bound, single-subunit enzy...

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Foilsithe in:Sci Rep
Main Authors: Rodrigues, Ana Paula C., Camargo, André F., Andjelković, Ana, Jacobs, Howard T., Oliveira, Marcos T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2018
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052043/
https://ncbi.nlm.nih.gov/pubmed/30022066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29150-x
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