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Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase

The xenotopic expression of the alternative oxidase AOX from the tunicate Ciona intestinalis in diverse models of human disease partially alleviates the phenotypic effects of mitochondrial respiratory chain defects. AOX is a non-proton pumping, mitochondrial inner membrane-bound, single-subunit enzy...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Rodrigues, Ana Paula C., Camargo, André F., Andjelković, Ana, Jacobs, Howard T., Oliveira, Marcos T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052043/
https://ncbi.nlm.nih.gov/pubmed/30022066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29150-x
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