ADAMTS13 deficiency exacerbates VWF-dependent acute myocardial ischemia/reperfusion injury in mice

Epidemiologic studies suggest that elevated VWF levels and reduced ADAMTS13 activity in the plasma are risk factors for myocardial infarction. However, it remains unknown whether the ADAMTS13-VWF axis plays a causal role in the pathophysiology of myocardial infarction. In the present study, we teste...

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Bibliografiske detaljer
Main Authors: Gandhi, Chintan, Motto, David G., Jensen, Melissa, Lentz, Steven R., Chauhan, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Thrombosis and Hemostasis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537314/
https://ncbi.nlm.nih.gov/pubmed/22983446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-440255
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