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ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice
BACKGROUND: ADAMTS13 cleaves hyperactive ultra-large von Willebrand factor (ULVWF) multimers into smaller and less active forms. It remains unknown whether VWF-mediated inflammatory processes may play a role in the enhanced brain injury due to ADAMTS13 deficiency. OBJECTIVE: We tested the hypothesis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419774/ https://ncbi.nlm.nih.gov/pubmed/22712744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04822.x |
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