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ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice
ADAMTS13, a metalloprotease, plays a pivotal role in preventing spontaneous microvascular thrombosis by cleaving hyperactive ultra large von Willebrand factor multimers into smaller, less active multimers. Reduced ADAMTS13 activity in plasma has been described in many diseases associated with system...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311260/ https://ncbi.nlm.nih.gov/pubmed/22123843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-376202 |
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