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The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation
ADAMTS13 is a multidomain protease that limits platelet thrombogenesis through the cleavage of von Willebrand factor (VWF). We previously identified 2 types of mouse Adamts13 gene: the 129/Sv-strain Adamts13 gene encodes the long-form ADAMTS13 having the same domains as human ADAMTS13, whereas the C...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2686194/ https://ncbi.nlm.nih.gov/pubmed/19109562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-169359 |
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