ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice

BACKGROUND: ADAMTS13 cleaves hyperactive ultra-large von Willebrand factor (ULVWF) multimers into smaller and less active forms. It remains unknown whether VWF-mediated inflammatory processes may play a role in the enhanced brain injury due to ADAMTS13 deficiency. OBJECTIVE: We tested the hypothesis...

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Bibliografiska uppgifter
Huvudupphovsmän: Khan, Mohammad Moshahid, Motto, David G., Lentz, Steven R., Chauhan, Anil K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419774/
https://ncbi.nlm.nih.gov/pubmed/22712744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04822.x
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