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Antitumor Agents 291 Expanded B-Ring Modification Study of 6,8,8-Triethyl Desmosdumotin B Analogues as Multidrug-Resistance Selective Agents

Drug usefulnessis frequently obstructed by the incidence of the multidrug resistance (MDR) phenotype and severe adverse effects. Exploiting collateral sensitive(CS)agents (in this case also called MDR-selective agents), which selectively target only MDR cells, is an emerging and novel approach to ov...

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Autors principals: Nakagawa-Goto, Kyoko, Bastow, Kenneth F, Ohkoshi, Emika, Morris-Natschke, Susan L, Lee, Kuo-Hsiung
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537172/
https://ncbi.nlm.nih.gov/pubmed/23293751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0444.1000101
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