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Chronic low dose UV exposure and p53 mutation: tilting the odds in early epidermal preneoplasia?
PURPOSE: This review addresses how mutation of the TP53 gene (p53) and ultraviolet light alter the behavior of normal progenitor cells in early epidermal preneoplasia. CONCLUSIONS: Cancer is thought to evolve from single mutant cells, which expand into clones and ultimately into tumors. While the mu...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537167/ https://ncbi.nlm.nih.gov/pubmed/22671441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2012.699697 |
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