Relationship of p53 Mutations to Epidermal Cell Proliferation and Apoptosis in Human UV-Induced Skin Carcinogenesis

Human skin is continually subjected to UV-irradiation with the p53 gene playing a pivotal role in repair of UV-induced DNA damage and apoptosis. Consequently, p53 alterations are early events in human UV-induced skin carcinogenesis. We studied 13 squamous cell carcinomas (SCC), 16 actinic keratoses...

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Detalhes bibliográficos
Main Authors: Einspahr, Janine G, Alberts, David S, Warneke, James A, Bozzo, Paul, Basye, Jenny, Grogan, Thomas M, Nelson, Mark A, Bowden, G Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Stockton Press 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508112/
https://ncbi.nlm.nih.gov/pubmed/10933063
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