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Interleukin 37 is a fundamental inhibitor of innate immunity

The function of interleukin 37 (formerly IL-1 family member 7) remains elusive. Expression of IL-37 in macrophages or epithelial cells imparted near complete suppression of pro-inflammatory cytokines, whereas the abundance of these cytokines increased with silencing of endogenous IL-37 in human bloo...

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Autors principals: Nold, Marcel F, Nold-Petry, Claudia A, Zepp, Jarod A, Palmer, Brent E, Bufler, Philip, Dinarello, Charles A
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537119/
https://ncbi.nlm.nih.gov/pubmed/20935647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1944
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