Dynamic Phosphorylation of Tyrosine 665 in Pseudopodium-enriched Atypical Kinase 1 (PEAK1) Is Essential for the Regulation of Cell Migration and Focal Adhesion Turnover

Pseudopodium-enriched atypical kinase 1 (PEAK1) is a recently described tyrosine kinase that associates with the actin cytoskeleton and focal adhesion (FA) in migrating cells. PEAK1 is known to promote cell migration, but the responsible mechanisms remain unclear. Here, we show that PEAK1 controls F...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bristow, Jeanne M., Reno, Theresa A., Jo, Minji, Gonias, Steven L., Klemke, Richard L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537006/
https://ncbi.nlm.nih.gov/pubmed/23105102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410910
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