Načítá se...

Critical Roles of Myc-ODC Axis in the Cellular Transformation Induced by Myeloproliferative Neoplasm-Associated JAK2 V617F Mutant

The acquired mutation (V617F) of Janus kinase 2 (JAK2) is observed in the majority of patients with myeloproliferative neoplasms (MPNs). In the screening of genes whose expression was induced by JAK2 (V617F), we found the significant induction of c-Myc mRNA expression mediated by STAT5 activation. I...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Funakoshi-Tago, Megumi, Sumi, Kazuya, Kasahara, Tadashi, Tago, Kenji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536786/
https://ncbi.nlm.nih.gov/pubmed/23300995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052844
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!