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Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: Antagonistic effects of Gβγ and protein kinase C
L-type voltage dependent Ca(2+) channels (L-VDCCs; Ca(v)1.2) are crucial in cardiovascular physiology. In heart and smooth muscle, hormones and transmitters operating via G(q) enhance L-VDCC currents via essential protein kinase C (PKC) involvement. Heterologous reconstitution studies in Xenopus ooc...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536727/ https://ncbi.nlm.nih.gov/pubmed/22990911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22016 |
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