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Toxin binding reveals two open state structures for one acid-sensing ion channel
Of the three principal conformations of acid-sensing ion channels (ASICs)—closed, open and desensitized—only the atomic structure of the desensitized conformation had been known. Two recent papers report the crystal structure of chicken ASIC1 in complex with the spider toxin psalmotoxin 1, and one o...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536724/ https://ncbi.nlm.nih.gov/pubmed/22990981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22154 |
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