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High Frequency of Herpesvirus-Specific Clonotypes in the Human T Cell Repertoire Can Remain Stable over Decades with Minimal Turnover

High-throughput T cell receptor sequencing on sequentially banked blood samples from healthy individuals has shown that high-frequency clonotypes can remain relatively stable for up to 18 years, with minimal inflation, deflation, or turnover. These populations included T cell expansions specific for...

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Bibliografiset tiedot
Päätekijät: Neller, M. A., Burrows, J. M., Rist, M. J., Miles, J. J., Burrows, S. R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536364/
https://ncbi.nlm.nih.gov/pubmed/23077319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02180-12
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