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A Complex Containing the CPSF73 Endonuclease and Other Polyadenylation Factors Associates with U7 snRNP and Is Recruited to Histone Pre-mRNA for 3′-End Processing

Animal replication-dependent histone pre-mRNAs are processed at the 3′ end by endonucleolytic cleavage that is not followed by polyadenylation. The cleavage reaction is catalyzed by CPSF73 and depends on the U7 snRNP and its integral component, Lsm11. A critical role is also played by the 220-kDa pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Xiao-Cui, Sabath, Ivan, Dębski, Jan, Kaus-Drobek, Magdalena, Dadlez, Michał, Marzluff, William F., Dominski, Zbigniew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536302/
https://ncbi.nlm.nih.gov/pubmed/23071092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00653-12
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