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U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem–loop binding protein
Cleavage of histone pre-mRNAs at the 3′ end requires stem–loop binding protein (SLBP) and U7 snRNP that consists of U7 snRNA and a unique Sm ring containing two U7-specific proteins: Lsm10 and Lsm11. Lsm11 interacts with FLASH and together they bring a subset of polyadenylation factors to U7 snRNP,...
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| Publicat a: | RNA |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5435866/ https://ncbi.nlm.nih.gov/pubmed/28289156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060806.117 |
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