U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem–loop binding protein

Cleavage of histone pre-mRNAs at the 3′ end requires stem–loop binding protein (SLBP) and U7 snRNP that consists of U7 snRNA and a unique Sm ring containing two U7-specific proteins: Lsm10 and Lsm11. Lsm11 interacts with FLASH and together they bring a subset of polyadenylation factors to U7 snRNP,...

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Publicado no:RNA
Main Authors: Skrajna, Aleksandra, Yang, Xiao-cui, Bucholc, Katarzyna, Zhang, Jun, Hall, Traci M. Tanaka, Dadlez, Michał, Marzluff, William F., Dominski, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435866/
https://ncbi.nlm.nih.gov/pubmed/28289156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060806.117
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